Abstract #0061
Validation of accelerated TE-Averaged Echo-Planar Spectroscopic Imaging in Healthy and HIV youths
Zohaib Iqbal 1 , Neil E. Wilson 1 , Brian L. Burns 1 , Margaret A. Keller 1 , and Michael Albert Thomas 1
1
University of California - Los Angeles, Los
Angeles, California, United States
The purpose of this study was to evaluate regional
metabolite differences in perinatally HIV-infected
youths using accelerated TE-averaged echo-planar
Spectroscopic Imaging (accelerated TEA-EPSI), which
acquires TE-averaged spectroscopic images from multiple
slices in a clinically feasible scan time. The results
show significantly increased Ch/Cr in the basal ganglia
and increased Glu/Cr in the occipital gray regions, as
well as a trend for decreased NAA/Cr in the frontal
white region in the brain of HIV-infected youths when
compared to that of healthy youths. This is consistent
with previous findings. Overall, this study demonstrates
the potential of accelerated TEA-EPSI for investigating
neurological diseases.
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