Abstract #4915
Slab registration as a first step towards hippocampus subparts high resolution imaging at 7T
Linda Marrakchi-Kacem 1,2 , Alexandre Vignaud 3 , Johanne Germain 1,2 , Julien Sein 4 , Thomas R. Henry 5 , Cyril Poupon 3 , Lucie Hertz-Pannier 3 , Stphane Lehricy 1,6 , Olivier Colliot 1,2 , Pierre-Franois Van de Moortele 4 , and Marie Chupin 1,2
1
UPMC-Paris6, CRICM, CNRS, UMR 7225, Inserm,
UMR-S975, ICM, Paris, France,
2
Aramis
project-team, Inria Paris-Rocquencourt, Paris, France,
3
NeuroSpin,
CEA, Gif-Sur-Yvette, France,
4
CMRR,
University of Minnesota, Minneapolis, MN, United States,
5
Department
of Neurology, University of Minnesota, Minneapolis, MN,
United States,
6
AP-HP,
Hpital de la Salptrire, CENIR, Paris, France
Imaging of the hippocampus subparts with high resolution
requires long acquisition time which can generate
movement artifacts inside the images. This problem can
be solved using multi-slab acquisitions which reduce
acquisition time but require an accurate registration
method to overcome inter-slab movement. We propose an
efficient registration procedure for interleaved slab
acquisitions. It consists in registering the slabs
containing gaps to a reference image with SPM8 and
homogenizing the intensities using synthetic phantoms.
This registration method was tested and validated on two
datasets acquired for hippocampus subparts imaging in
two different centers for a total of 34 subjects. It
proved robust for both multi-slab protocols.
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