Abstract #4460
The importance of correcting for B0-drift-induced global signal decrease in diffusion MRI
Sjoerd B. Vos 1 , Chantal M.W. Tax 1 , Fredy Visser 2 , Peter R. Luijten 2 , Alexander Leemans 1 , and Martijn Froeling 2
1
Image Sciences Institute, University Medical
Center Utrecht, Utrecht, Utrecht, Netherlands,
2
Department
of Radiology, University Medical Center Utrecht,
Utrecht, Utrecht, Netherlands
B0-drift-induced global signal decrease in DWI data
causes a significant influence on the estimation of
diffusion parameters. Quantitative diffusion metrics (FA
and mean kurtosis) as well as directional information
(first eigenvectors in DTI) are affected by this
artifactual signal decrease during the scan session. By
interspersing the non-diffusion-weighted images
throughout the session, the signal decrease can be
estimated and compensated before processing, minimizing
the detrimental effects on all further analyses.
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