Abstract #4432
Magnetic Resonance Microscopy of the Drosophila Brain at 10 Micron Isotropic Resolution
Choong Heon Lee 1,2 , Stephen J Blackband 1,2 , and Fernandez-Funez Pedro 1,3
1
Neuroscience, University of Florida,
Gainesville, FL, United States,
2
McKnight
Brain Institute, Gainesville, FL, United States,
3
Neurology,
University of Florida, FL, United States
Understanding the complex brain architecture and
functional connectivity using MRI has been a major
interest in neuroscience. Based on the capability of MR
microscopy to visualize the mammalian and human cells,
the desire to map the entire human brain circuit at the
resolution high enough to visualize cell-level
structures is becoming a reality. Studies of a simpler
brain, i.e. Drosophila, are significant due to its high
genetic tractability together with high degree of
conservation with humans at the genetic and cellular
levels. To visualize the neuronal circuitry in the
brain, we acquired MRM of it at 10 m isotropic
resolution.
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