Abstract #4431
Integrated Phantom Analysis of Perfusion, Diffusion, and Fluctuation MRI
Naoki Ohno 1 , Tosiaki Miyati 1 , Tomohiro Chigusa 1 , Hikaru Usui 1 , Noam Alperin 2 , Shinnosuke Hiratsuka 1 , Akihiro Asano 1 , Hirohito Kan 3 , Satoshi Kobayashi 1 , Toshifumi Gabata 1 , and Osamu Matsui 1
1
Kanazawa University, Kanazawa, Japan,
2
University
of Miami, FL, United States,
3
Nagoya
City University Hospital, Nagoya, Japan
To clarify relations and mechanisms among
blood-perfusion, water-diffusion, water-fluctuation, and
biomechanics of the intracranial tissue, we developed an
original cranial phantom for magnetic resonance imaging.
The new cranial phantom consisted of a high-density
polypropylene filter with intra- and extra-filter
spaces, and a capacitor space, which were filled with
water at 17 degrees centigrade. These correspond to a
brain parenchyma, artery and vein, and cerebrospinal
fluid space, respectively. Our original phantom makes it
possible to clarify relations and mechanisms among
blood-perfusion, water-diffusion, water-fluctuation, and
biomechanics of intracranial tissue. Perfusion,
diffusion, fluctuation, and biomechanics of the
intracranial tissue interact in diverse ways.
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