Abstract #3674
A motion-robust sequence for combined thermometry and T2-mapping to guide and assess tissue damage during thermal therapies
Chang-Sheng Mei 1 , Renxin Chu 1 , Lawrence P Panych 1 , and Bruno Madore 1
1
Department of Radiology, Harvard Medical
School, Brigham and Women's Hospital, Boston, MA, United
States
Tissue damage is conventionally detected by thermal
dose, which depends on heating history and can thus
become fairly erratic in the presence of motion. The
main purpose of this study was to detect tissue damage
not only by thermal dose but also through changes in T2,
in the presence of motion. We employed a dual-pathway
sequence to simultaneously map temperature changes and
T2 during focused ultrasound experiments that were
performed in turn with or without motion. The presence
of motion very much affected the phase-based temperature
measurements but not nearly as much the magnitude-based
T2 measurements.
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