Abstract #3673
Phantom validation of temperature mapping using fat-water MRI with explicit fitting of water peak location
E. Brian Welch 1,2 , Aliya Gifford 2,3 , and Theodore F. Towse 2,4
1
Radiology and Radiological Sciences,
Vanderbilt University, Nashville, TN, United States,
2
Institute
of Imaging Science, Vanderbilt University, Nashville,
TN, United States,
3
Chemical
and Physical Biology Program, Vanderbilt University,
Nashville, TN, United States,
4
Physical
Medicine and Rehabilitation, Vanderbilt University,
Nashville, TN, United States
This research demonstrates MRI-based thermometry in
fat-water phantoms by explicitly modeling the
temperature-dependent water peak frequency shift in the
fat-water signal equation. Besides temperature
monitoring of mixed fat/water tissue during
interventional applications, this method is well suited
for studying brown adipose tissue. The technique was
tested on phantoms with nominal fat fractions of 0, 10,
20, 30, 40, 60 and 100 percent undergoing heating and
cooling with validation using fiber optic temperature
probes. MRI-based measurements followed closely the
probe measurements except for areas with fat-water
mapping errors or in phantoms with only one species,
i.e. 0% or 100% fat.
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