Abstract #3101
Repeatibility of M, BOLD, CBF and CMRO 2 for cognitive tasks at 7 Tesla
Steffen N Krieger 1,2 , Claudine J Gauthier 2 , Dimo Ivanov 3 , Laurentius Huber 2 , Elisabeth Roggenhofer 2 , Bernhard Sehm 2 , Robert Turner 2 , and Gary F Egan 1
1
Monash Biomedical Imaging, Monash
University, Melbourne, Victoria, Australia,
2
Max-Plank
Institute for Human Cognitive and Brain Sciences,
Leipzig, Saxonia, Germany,
3
Maastricht
University, Netherlands
Calibrated BOLD might be a powerful alternative to
classic functional MRI techniques especially as CMRO2
has been found to be more spatially specific when
mapping cerebral functional activation compared to BOLD.
However, the application of calibrated BOLD at
ultra-high field strengths and in combination with more
complex cognitive study designs might have been
inhibited by the limited knowledge about stability. This
study provides evidence that CMRO2 is a reliable
biomarker for cognitive studies even when used at
ultra-high magnetic fields. The calibrated BOLD
technique might be a viable alternative to classic BOLD
approaches.
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