Abstract #2147
Liver iron content measurement using quantitative susceptibility mapping
Alexey Dimov 1,2 , Pascal Spincemaille 3 , Carlo Salustri 3 , Tian Liu 4 , Bo Xu 1,2 , and Yi Wang 1,2
1
Biomedical Engineering, Cornell University,
Ithaca, NY, United States,
2
Radiology,
Weill Cornell Medical College, New York, NY, United
States,
3
Radiology,
Weill Cornell Medical College, NY, United States,
4
MedimageMetric
LLC, NY, United States
The quantification of iron content is traditionally
performed by R2* mapping, which is sensitive to imaging
parameters and affected by large field inhomogeneity
such as near the liver-lung interface. In this abstract,
we propose the use of a breath-hold 3D spiral multi-echo
flow compensated sequence combined with an adaptive
fat-water separation method to obtain liver iron content
based on magnetic susceptibility.
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