Abstract #1408
Direct evaluation of MR-derived attenuation correction maps for PET/MR of the mouse myocardium
Eleanor Evans 1 , Guido Buonincontri 1 , Rob C Hawkes 1 , Richard E Ansorge 2 , T. Adrian Carpenter 1 , and Stephen J Sawiak 1,3
1
Wolfson Brain Imaging Centre, University of
Cambridge, Cambridge, United Kingdom,
2
Department
of Physics, University of Cambridge, Cambridge, United
Kingdom,
3
Behavioural and Clinical
Neurosciences Institute, University of Cambridge,
Cambridge, United Kingdom
Attenuation correction (AC) must be applied to provide
quantitative measurements of Positron Emission
Tomography (PET) tracer activity concentrations. The
gold standard AC method involves passing a transmission
source around the subject and surrounding scanner
equipment. Due to the limited space in PET/MR scanners,
MR-derived AC (MRAC) must be used instead. This is
problematic as MR signals are not directly related to
the amount of gamma radiation absorbed. By comparing to
gold standard transmission scans, we found a single
tissue region MRAC segmentation approach, derived from
whole body MRI, provided accurate myocardial SUV values
in mice.
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