Abstract #1246
Intravoxel Incoherent Motion (IVIM) MR Imaging of Degenerated Intervertebral Lumbar disks: an initial experience
Niu Gang 1 , Liu Zhe 1 , Du Yong Hao 1 , and Yang Jian 1,2
1
Department of Radiology, the first
affiliated hospital of medical college, Xian Jiaotong
University, Xi'an, Shaanxi, China,
2
Department
of Biomedical Engineering, School of Life Science and
Technology, Xi' an Jiaotong University, Xi'an, Shaanxi,
China
The aim of this study is to assess the feasibility of
using intravoxel incoherent motion(IVIM) MRI in vivo to
detect intervertebral disk degeneration(IVDD). 23
patients (14 men and 9 women; mean age 40 years; median
age 47; age range 21~73 years) with low back pain or
sciatica underwent IVIM MRI and T2 weighted images
(T2WIs). It was showed that the pure diffusion ADClow of
disk decrease with increased the Pfirrmann grades based
on T2WI in this study, which indicated the decreased
real diffusivity of free waterin IVDD. We also observed
increased pseudodiffusion coefficient ADCfast values of
AF with increased Pfirrmann grades,.The results
demonstrated not only the significant differences in
ADCfast of NP between grade I and IV, grade II and IV
(ANOVA, P0.05), but also the significant differences
in ADCfast of AF between grade I and IV, II and IV, III
and IV (ANOVA, P0.05), which suggested an increasing
microcapillary perfusionin IVDD. In sum, IVIM MR imaging
may provide an objective and non-invasive biomarker for
estimating diffusivity and microcapillary perfusion in
IVDD.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
