Abstract #0109
Multiplatform reproducibility of 3D carotid vessel wall MRI
Niranjan Balu 1 , Jie Sun 1 , Daniel S. Hippe 1 , David Zhu 2 , Seong-Eun Kim 3 , John Roberts 3 , J. Kevin DeMarco 2 , Dennis L. Parker 3 , David Saloner 4 , Michael V. McConnell 5 , Chun Yuan 1 , and Thomas S. Hatsukami 1
1
Radiology, University of Washington,
Seattle, WA, United States,
2
Radiology,
Michigan State University, Lansing, MI, United States,
3
Radiology,
Utah Center for Advanced Imaging Research, University of
Utah, Salt Lake City, UT, United States,
4
Radiology,
University of California San Francisco, San Francisco,
CA, United States,
5
Stanford
University, CA, United States
Large coverage 3D isotropic vessel MRI has recently been
proposed for carotid atherosclerotic plaque
characterization. Use of a multicontrast 3D MRI protocol
for serial MRI studies of atherosclerosis requires
standardized protocols across multiple scanner platforms
for use in multicenter studies. Reproducibility of
plaque measurements has not been established in a
multicenter setting. We demonstrate using patients with
50-79% stenosis that a standardized 3D carotid MRI
protocol can provide reproducible measurement across
three major scanner platforms (GE, Philips and Siemens).
Plaque burden measurements and identification of plaque
components showed good to excellent reproducibility
comparable to traditional 2D multicontrast vessel wall
MRI.
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