Matthias Alexander
Dieringer1, 2, Marcel Prothmann2, Florian
von Knobelsdorff-Brenkenhoff1, 2, Andreas Greiser3,
Christina Eichhorn, Thoralf Niendorf1, 4, Jeanette
Schulz-Menger1, 2
1Berlin
Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular
Medicine, Berlin, Germany; 2Working Group on Cardiovascular
Magnetic Resonance, Experimental and Clinical Research Center (ECRC), Berlin,
Germany; 3Siemens AG, Erlangen, Germany; 4Experimental
and Clinical Research Center (ECRC), a cooperation of the Charit Medical
Faculty and the Max-Delbrueck Center for Molecular Medicine, Berlin, Germany
Cardiovascular MR (CMR) offers the unique capability for non-invasive characterization and differentiation of myocardial tissue. Viability imaging including detection of myocardial infarction is usually based on late Gadolinium enhanced (LGE) imaging. To deliver more precise information about pathogenesis and classification of cardiac disorders, quantitative MR imaging is promising to characterize stage and progress of complex pathophysiological processes. We propose a method that combines quantitative T1 and semi quantitative perfusion imaging to enable intra-individual assessment of impact and progress of cardiac diseases on myocardial tissue viability. The technique is presented on two patients with chronic myocardial infarction.