Abstract #4222

Intervertebral Disc CEST Imaging with Improved Reliability Using Reduced-FOV TSE

Qi Liu¹,², Ning Jin³, Zhaoyang Fan¹, Yutaka Natsuaki⁴, Wafa Tawackoli¹, Dan Gazit¹, Gadi Pelled¹, Debiao Li¹,⁵

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; ²Biomedical Engineering, Northwestern University, Chicago, IL, United States; ³Siemens Medical Solutions, Columbus, OH, United States; ⁴Siemens Healthcare, Los Angeles, CA, United States; ⁵University of California, Los Angeles, los angeles, CA, United States

A reduced-field-of-view (rFOV) TSE method is used to reliably measure IVD gagCEST signal in vivo by reducing bowel movement artifacts on a 3.0T clinical scanner. The proposed method is verified by a phantom study, and is compared with the conventional full-FOV CEST technique on nine volunteers.