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Abstract #3477

Non-Gaussian Diffusion Weighted Imaging for Assessing Diurnal Changes in Intervertebral Disc Composition

Masaki Katsura1, Yuichi Suzuki2, Junichi Hata2, Hiroki Sasaki1, 2, Hiroyuki Akai1, Wataru Gonoi1, Harushi Mori1, Akira Kunimatsu1, Yoshitaka Masutani1, Masaaki Hori3, Shigeki Aoki3, Kuni Ohtomo1

1Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; 2Radiology, The University of Tokyo Hospital, Tokyo, Japan; 3Radiology, School of Medicine, Juntendo University, Tokyo, Japan


In the present study, changes in T2 values and diffusion metrics of QSI data in IVDs before and after a diurnal load cycle were investigated. T2, ADC, and RMSD metrics in the evening were significantly lower than those in the morning, while the AKC value showed a