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Abstract #3476

Accelerated T1rho Relaxation Quantification in Intervertebral Disc Using Limited Spin-Lock Times

Pu-Xuan Lu1, Feng Zhao2, Jing Yuan2, Greta S.P. Mok3, James F. Griffith2, Yi-Xiang Wang2

1Department of Radiology, the Shenzhen Third People's Hospital, Shenzhen, Guangdong, China; 2Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong; 3Department of Electrical and Electronics Engineering, University of Macau, Macau, Macau


For traditional T1rho MR imaging applications like spine, multiple spin-lock times (SLT), often ~5 SLTs, are used to ensure the accuracy and robustness of T1rho mapping. The reduction of the applied SLT numbers is an apparent strategy to enhance T1rho imaging efficiency as long as the accuracy and reliability of T1rho mapping could be maintained. In this study, the agreement of liver T1rho measurements using 3 and 5 SLT points was evaluated. We found that using 3 SLTs of 1, 20, and 60 ms can be an acceptable alternative for disc T1rho measurement.