Elodie Andr1,
Christophe Phillips1, 2, Ezequiel Farrher3,
Ivan I. Maximov4, Farida Grinberg3, Nadim Jon Shah4,
5, Evelyne Balteau1
1Cyclotron
research center, University of Lige, Lige, Belgium; 2Department
of Electrical Engineering and Computer Science, University of Lige, Lige,
Belgium; 3Institute of Neuroscience and Medicine - 4, Forschungszentrum
Juelich, Juelich, Germany; 4Institute of Neuroscience and Medicine
- 4, Forschungszentrum Juelich GmbH, Juelich, Germany; 5Department
of Neurology, Faculty of Medicine, RWTH Aachen University, JARA, Aachen,
Germany
The use of high b-values in diffusion kurtosis imaging makes the derived parameters very sensitive to low signal to noise. Here we show the dependence of mean kurtosis on SNR and demonstrate that noise correction is a necessary step, leading to more reproducible metrics.