Abstract #3045

Effect of NMDA-Receptor Inhibition on Relative Cerebral Blood Flow to the Hippocampus and Medial Prefrontal Cortex: A Placebo Controlled Repeated Measures Study of Ketamine in Healthy Young Men

Najmeh Khalili Mahani¹, Marieke Niesters¹, Matthias J.P. van Osch², Albert Dahan¹

¹Anesthesiology, Leiden University Medical Center, Leiden, Netherlands; ²Radiology, Leiden University Medical Center, Leiden, Netherlands

Pseudocontinuous ASL (pCASL) reveals regional effects of ketamine on relative cerebral blood flow in the hippocampus, basal ganglia, cerebellum and medial visual and prefrontal cortical regions.