Abstract #2981

ex vivo MRI of Carotid Plaque Excised by Endoarterectomy: Correlation Between T1 and Histologically Assessed Age and Degree of Hemorrhage in Lipid Rich Necrotic Core

Naoaki Yamada¹, Yoshiaki Morita¹, Koji Iihara², Hatsue Ishibashi-Ueda³, Masahiro Higashi¹, Hiroaki Naito

¹Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; ²Nuerosurgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; ³Pathology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Relationship between high signals on T1-weighted imaging and age of intraplaque hemorrhage is not sufficiently solved. Sixty-four sections from 16 specimens excised by endoarterectomy were studied to compare ex vivo MRI and histology. In the 64 sections, 46 lipid rich necrotic cores (LRNCs) were identified. Ex vivo MRI was performed to make a T1 map on a 1.5 T system. After MRI, the specimens were processed for pathology and stained by HE, MT and Anti-glycopholin A antibody. In the results, T1 of LRNC with chronic hemorrhage was short that was similar to those with recent hemorrhage.