Prediction and Assessment of Response to Renal Artery Revascularization with Dynamic Contrast-Enhanced MRI: A Pilot Study

Su Wei Lim¹, Constantina Chrysochou², David L. Buckley¹, Philip A. Kalra², Steven Sourbron¹

The purpose of this study is to assess the potential of DCE-MRI measurements of renal function and perfusion to predict and evaluate functional outcome after renal artery revascularization in humans. 16 patients with renal artery stenosis underwent DCE-MRI and radioisotope measurement of single-kidney GFR at baseline, and 4 months after revascularization. Results show that DCE-MRI has the potential to replace radioisotopes for planning and follow-up of renal artery revascularisation, and may improve patient selection through the additional information on vascularity. Specifically, the data suggest that well-vascularised kidneys with low extraction fractions are most likely to benefit.