1Biomedical
Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Siemens
AG, Erlangen, Germany; 3Radiology, University Hospitals Case Medical
Center, Cleveland, OH, United States; 4Radiology, Case Western
Reserve University, Cleveland, OH, United States; 5Siemens Medical
Solutions, USA Inc., Malvern, PA, United States
Loud acoustic noise is a major cause of patient discomfort. It is mainly introduced during gradient switching, and many efforts have been made to address this issue. Some MR manufacturers encloses the whole gradient coil in a vacuum environment to reduce the noise significantly, increasing manufacturing costs. We present another approach without hardware modification, which relies solely on the optimization of pulse sequences to realize noise reduction for various standard clinical protocols. No significant degradation of imaging time or image quality was observed. With such an approach, for certain specific sequences, acoustic noise can be reduced almost to ambient level.