Rajakumar Nagarajan1, Whitney B. Pope1, Robert Prins2, Noriko Salamon1, Manoj K. Sarma1, Linda Liau2, M.Albert Thomas1
1Radiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA, United States; 2Neurosurgery, University of California Los Angeles (UCLA), Los Angeles, CA, United States
Proton (1H) MRS plays an important role in the diagnosis of brain tumors. The ability to discriminate among major types of primary brain tumors is critical in formulating a precise and effective treatment plan. The role of MRS in the clinical decision-making process is in distinguishing different grades of brain tumors on the basis of differences in metabolite ratios. We have quantified major metabolites using MRS in tumor and normal appearing brain and their values were compared between various grades.