Huimin Wu1, Walter F. Block2, Patrick A. Turski3, Charles A. Mistretta1, Kevin M. Johnson1
1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin-Madison; 3Radiology, University of Wisconsin-Madison
4D intracranial angiography with a pseudo continuous Arterial Spin Labeling (PCASL) tagging scheme and accelerated radial sampling pattern has been implemented. A feasibility study has been done on healthy volunteers and AVM patients and time-resolved images were acquired with temporal resolution of 200 msec. It has been demonstrated that the dynamic PCASL-VIPR technique can acquire a time series of dynamic inflow images with high 3D isotropic spatial resolution, and whole head coverage in a 7-minute scan. Quantitative analysis using time-of-arrival maps can also be performed on the time-resolved images.