Abstract #0528

Clinical Evaluation of Peripheral Non-Contrast Enhanced MR Angiography (NCE-MRA) Using Steady-State Free Precession (SSFP) & Flow Sensitive Dephasing (FSD) in Diabetes

Na Zhang¹, Zhaoyang Fan², Fei Feng³, Pengcheng Liu⁴, Xin Liu¹, Dehe Weng⁵, Renate Jerecic, Yongming Dai⁵, Hairong Zheng¹, Debiao Li²

¹Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; ²Cedars Sinai Medical Center and University of California, Los Angeles, CA, United States; ³Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China; ⁴3Department of Radiology, Peking University Shenzhen Hospital; ⁵Siemens Healthcare, Shanghai, China

A novel peripheral non-contrast enhanced MR Angiography (NCE-MRA) using SSFP and flow-sensitive dephasing (FSD) was evaluated for detecting peripheral arterial disease in diabetes. Forty-five patients underwent contrast enhanced MRA (CE-MRA) and NCE-MRA in calf and foot on a 1.5T MR system. Image quality and significant arterial stenosis50%was assessed by two experienced radiologists. The technique demonstrated a comparable percentage of diagnostic arterial segments and image quality with CE-MRA, and a high diagnostic accuracy for detecting significant arterial stenosis. It can be used as an alternative method for the detection of lower-extremity arterial disease in diabetic patients.