Abstract #4270

Classification of Tissue Oxygenation Properties Based on Simultaneous Dynamic δR1 & δR2* D(C)O2E-MRI

Stefanie Remmele¹, Andreas Mller², Frank Trber², Ingobert Wenningmann³, Marec von Lehe⁴, Juergen Gieseke^2,5, Sebastian Flacke^2,6, Winfried A. Willinek², Hans H. Schild², Jochen Keupp¹, Petra Mrtz²

¹Philips Research Laboratories, Hamburg, Germany; ²Department of Radiology, University of Bonn, Bonn, Germany; ³Department of Anesthesiology, University of Bonn, Bonn, Germany; ⁴Department of Neurosurgery, University of Bonn, Bonn, Germany; ⁵Philips Healthcare, Best, Netherlands; ⁶Department of Radiology, Lahey Clinic, Tufts University Medical School, MA, United States

We devised an approach to simultaneous and dynamic dR1, dR2* quantification to increase the specificity of O₂ and CO₂ enhanced MRI. The technique is applied to patients with cerebral tumors and a volunteer. The multi-parametric findings are related to tissue-specific oxygenation properties.