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Abstract #4225

Diffusivity Alterations in Temporal Lobe Epilepsy

Paula Bezerra Diniz1,2, Carlos Ernesto Garrido Salmon2,3, Tonicarlo Velasco1,2, Americo Ceiki Sakamoto1,2, Joo Pereira Leite1,2, Antonio Carlos Santos2,4

1Neuroscience & Behavior, FMRP, University of So Paulo, Ribeiro Preto, SP, Brazil; 2CInAPCe (Cooperao Interinstitucional de Apoio a Pesquisas sobre o Crebro), Ribeiro Preto, SP, Brazil; 3Physics & Mathematics, FFCLRP, University of So Paulo, Ribeiro Preto, SP, Brazil; 4Internal Medicine, FMRP, University of So Paulo, Ribeiro Preto, SP, Brazil


In this study, we combined the use of fractional anisotropy (FA), mean diffusivity (Dave), parallel diffusivity (Dpar), and perpendicular diffusivity (Dper) to localize the regions where occur axonal lesion and demyelination in patients with TLE.