Abstract #4163

Diminished Resting-State Functional Connectivity in Lateral Occipital Cortex in Early HIV Infection

Paul Foryt^1,2, Xue Wang¹, Renee Ochs¹, Jae-Hon Chung^1,2, Ying Wu^1,3, Todd Parrish¹, Ann B. Ragin^1,3

¹Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States; ²Engineering, Northwestern University, Evanston, IL, United States; ³Radiology, NorthShore University HealthSystem, Evanston, IL, United States

Using resting state functional connectivity MRI, thirty subjects, fifteen HIV+ and fifteen controls, were scanned on a 3.0T Siemens Trio to evaluate connectivity between brain networks. ICA component analysis was used on the collected data, finding that scanned HIV+ subjects had diminished connectivity within the lateral occipital cortex network, one of the main resting state networks. This network has been associated with visuospatial attention.