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Abstract #3542

Exchange Dynamics of a Cryptophane-Based Xenon Molecular Sensor

Richard Matthew Ramirez1,2, Todd K. Stevens1,2, Monica A. Smith3,4, David E. Wemmer1,4, Alexander Pines1,2

1Department of Chemistry, University of California, Berkeley, Berkeley, CA, United States; 2Materials Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States; 3Biophysics Graduate Group, University of California, Berkeley, United States; 4Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States


The exchange dynamics of a xenon molecular sensor based on cryptophane-A were elucidated by modeling the signal decay generated by (CEST) against the McConnell-Bloch equations to determine xenon dissociation rates from cryptophane-A