Gary Cowin1, Nyoman Dana Kurniawan1,
Paul Sved2,3, Geoff Watson4, Roger Bourne5
1Centre for Advanced Imaging,
the University of Queensland, Brisbane, Queensland, Australia; 2Department
of Surgery, Faculty of Medicine, University of Sydney, Sydney, New South
Wales, Australia; 3Department of Urology, Royal Prince Alfred
Hospital, Sydney, New South Wales, Australia; 4Department of
Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, New South Wales,
Australia; 5Discipline of Medical Radiation Sciences, Faculty of
Health Sciences, University of Sydney, Sydney, New South Wales, Australia
Current clinical identification of prostrate cancer tissue using MRI is limited by the resolution and contrast, which has yet to approach the gold standard of histopathology of biopsy tissue. In this work, we present high-resolution diffusion and micro-MR imaging of prostrate biopsy samples in order to understand the underlying properties of the normal and cancer tissue contrast, and their correlation with low-resolution clinical MRI scans.