Jelena Curcic1, Matthias Sauter2,
Werner Schwizer2, Peter Boesiger1, Andreas Steingoetter1,2
1Institute for Biomedical
Engineering, University & ETH, Zurich, Switzerland; 2Division
of Gastroenterology & Hepatology, University Hospital Zurich, Zurich, Switzerland
Gastric emptying, distention, intragastric secretion and mixing are important factors in pathogenesis of gastro-intestinal (GI) diseases such as gastro-esophageal reflux disease (GERD). A formerly described method, for simultaneous T1 mapping and imaging was optimized and validated for free breathing gastric imaging. The optimized sequence (GOLD) was used in-vivo to simultaneously detect intragastric secretion and mixing as well as gastric emptying during free breathing. This pilot study shows the feasibility of the GOLD sequence to detect multiple gastric parameters in one single free breathing period of maximally 2 min and emerges as a versatile tool for diagnostic GI MRI.