Diffusion-Weighted MRI for the Zonal Characterization of Liver Tumors

Mathilde Wagner^1,2, Sabrina Doblas², Jean-Luc Daire^1,2, Helena Leitao^1,2, Philippe Garteiser², Valrie Vilgrain^1,2, Ralph Sinkus², Bernard Edgar Van Beers^1,2

The aim of this study was to assess if DW-MRI with separate measurements of ADC mono, ADC slow, and ADC fast could be used to differentiate between viable, fibrotic and necrotic regions within liver tumors. In contrast to ADC mono and ADC fast, ADC slow differed significantly between the three tumor regions. These results suggest that when using DW-MRI for the characterization and follow-up during treatment of liver tumors, ADC slow rather than ADC mono should be used.