Improved Motion-Sensitized Driven-Equilibrium (IMSDE) Prepared 3D GRASE for High Field Magnetic Resonance Imaging of Carotid Artery Wall

Linqing Li¹, Alistair C. Lindsay², Matthew D. Robson¹, Peter Jezzard¹

Recently, an alternative black blood preparation technique of improved MSDE (iMSDE) has been proposed for vessel wall imaging. In this study, we combine the iMSDE black-blood (BB) module with a 3D GRASE imaging readout to create a robust clinically relevant protocol that is more time efficient in its data acquisition, less demanding in RF power deposition, and with improved BB characteristics at high field, in order to better differentiate vessel wall from lumen. T1, T2 and proton density weighted 3D GRASE images were acquired for comparison with the corresponding images from double inversion-recovery (DIR) and iMSDE 2D TSE techniques.