Abstract #2615

k-Space Sampling Approaches using TWIST: Implications for Dynamic Contrast Acquisitions

Xin Li¹, John W. Grinstead², Cecily V. Bishop³, Ian J. Tagge¹, Richard L. Stouffer^3,4, William D. Rooney¹, Gerhard Laub⁵

¹Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States; ²Siemens Healthcare, Portland, OR, United States; ³Division of Reproductive Sciences, ONPRC, Oregon Health & Science University, Portland, OR, United States; ⁴Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, United States; ⁵Siemens Healthcare, San Francisco, CA, United States

Time-resolved angiography with stochastic trajectories (TWIST) pulse sequence offers a practical and flexible way to perform sub-second, time-sequential 3D measurements. It is often used in combination with contrast injection to provide dynamic clinical information. Using a primate model (rhesus macaque) and simulated data therein, we investigated TWIST center of k-space updating strategy on Dynamic-Contrast-Enhanced (DCE) MRI signal time-course and image.