Cluster-Based Statistics Along White Matter Tracts

Demian Wassermann¹, Peter Savadjiev¹, Yogesh Rathi¹, Sylvain Bouix¹, Marek Kubicki¹, Ron Kikinis¹, Martha Shenton¹, Carl-Fredrik Westin¹

We present a method for cluster-based analysis along white matter tracts. The method shows increased sensitivity with respect to state-of-the-art methods while retaining mathematical soundness. We prove our method on a specific white matter bundle in a population of 18 schizophrenic subjects and 23 healthy controls.