Fat-Referenced MR Thermometry using 3-Echo Phase-Based Fat Water Separation Method

Lorne Hofstetter¹, Desmond Yeo¹, W. Thomas Dixon¹, Cynthia Davis¹, Thomas K. Foo¹

Accurate and stable MR thermometry is critical for interventional procedures such as RF hyperthermia and MR guided focused ultrasound therapy. In this work we present a 3-echo fat-referenced thermometry technique that reduces measurement error caused by time-varying changes in the underlying B0 field. This technique was validated in a cream cooling experiment (δT = 8.4C) where deviations between MR and fiber-optic temperature probe measurements were less than 0.28C.