Abstract #1373

Characterization of Myocardial T1 & Partition Coefficient as a Function of Time After Gadolinium Delivery in Healthy Subjects

Kelvin Chow¹, Jacqueline Flewitt², Jordin Green³, Matthias Friedrich^2,4, Richard Thompson¹

¹Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; ²Stephenson CMR Centre at the Libin Institute of Alberta, Department of Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada; ³Siemens Healthcare, Calgary, Alberta, Canada; ⁴Department of Radiology, University of Calgary, Calgary, Alberta, Canada

Myocardial and blood T₁ mapping was performed in 9 healthy subjects using a custom saturation recovery SSFP sequence on a single mid-ventricular short axis slice at 1.5T. Images were acquired at baseline and repeated at one-minute intervals following a gadolinium bolus injection and the blood-tissue partition coefficient was derived at each time point to determine the time-course relationship. At 15 min post contrast, average myocardial T₁ was 71938ms and lambda was 0.390.05. Over the 1015 minute post contrast window, myocardial T₁ values increased by 6% and the derived partition coefficient increased by only 1%.