Dynamic Contrast-Enhanced MRI in Rectal Tumours Initial Reproducibility Measurements at 3T with & Without Bowel Relaxant

Geoff Charles-Edwards^1,2, Jyoti Parikh¹, Nyree Griffin¹, Robert Johnstone¹, David Landau¹, Andrew Gaya¹

This work reports on initial reproducibility results from dynamic contrast enhanced MRI of rectal cancers at 3T, and compares results from patient with and without the administration of a bowel relaxant. The significant effect of bowel motion on DCE-MRI data and subsequent PK modelling is demonstrated.