Abstract #0832

Uterine Fibroids: Quantitative Assessment of Baseline T1, ADC & Microvascular Properties with T1w DCE-MRI

Lucy Elizabeth Kershaw¹, Yuexi Huang¹, Hallie Taylor^2,3, Elizabeth David², Kullervo Hynynen^1,4, Greg Stanisz^1,4, Laurent Milot^2,3

¹Imaging Research, Sunnybrook Research Institute, Toronto, Ontario, Canada; ²Radiology, Sunnybrook Research Institute, Toronto, Ontario, Canada; ³Medical Imaging, University of Toronto, Toronto, Ontario, Canada; ⁴Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Uterine fibroids are benign masses affecting ~20% of women of reproductive age, resulting in poor quality of life due to pelvic pain and dysmenorrhea. The success of treatments such as high intensity focused ultrasound depends on the perfusion of the fibroid, therefore a baseline assessment of the fibroid properties is important in the selection of the most appropriate treatment on a case-by case basis. Although the appearance on T₂w images has been documented, quantitative assessment of fibroid properties has been rare. In this study, ADC, T₁ measurements and DCE-MRI parameters derived from two different models are presented.