MR Spectroscopy of Endometrial Cancer - Initial Results at 3T

Geoff Charles-Edwards^1,2, Robert Johnstone¹, Sarah Natas¹, Audrey Jacques¹

Endometrial carcinoma is the most common gynaecological malignancy in Western countries. Conventional grading and staging by biopsy and imaging does not always correspond with the final histological grade determined post-hysterectomy. This results in some patients having less aggressive initial surgery, while others will have unnecessary extensive lymph node dissection. Consequently there is a need for additional information to improve preoperative assessment. This work describes some initial results from MR spectroscopy at 3T providing metabolic information about endometrial cancer that may aid in preoperative assessment of disease.