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Abstract #0375

Simultaneous Functional & Quantitative ASL: An Optimal Tool for Imaging Ongoing Pain States

Jingyi Xie1, Andy Segerdahl1,2, Irene Tracey1,3, Peter Jezzard1

1Nuffield Dept of Clinical Neurosciences (FMRIB Centre), University of Oxford, Oxford, United Kingdom; 2Nuffield Dept of Clinical Neurosciences (Anaesthetics), University of Oxford, Oxford, United Kingdom; 3Nuffield Dept of Clinical Neurosciences (Anaesthetics), University of Oxford, , Oxford, United Kingdom


In this study we implemented a novel whole brain ASL method that is capable of detecting functional neuronal activity whilst simultaneously obtaining absolute quantification of key physiological parameters such as cerebral blood flow (CBF) and arterial arrival time (Δt). This is the first demonstration of such an ASL approach within a pain imaging context.