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Abstract #0374

Alteration of Cerebral Blood Flow Values in Children with Cerebral Palsy using 3D Pseudocontinuous Arterial Spin Labeling: Its Correlation with DTI Metrics

Bhaswati Roy1, Vimal Paliwal2, Puneet Goel3, Siddhant Kumar1, Ram Kishan Singh Rathore4, Sanjay Verma4, Rakesh Kumar Gupta1

1Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 2 Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 3Department of Anaesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 4Department of Mathematics & Statistics, Indian Institute of Technology, Kanpur, Kanpur, Uttar Pradesh, India


We report significantly increased CBF in 12 children with cerebral palsy in certain white matter regions which was associated with decrease in FA. Significant inverse correlation observed between FA and CBF values suggests that CBF increase in these abnormal FA regions is an attempt by the body to improve neuronal plasticity. We conclude that ASL based CBF may be used as non invasive marker of brain plasticity in future.