Huyen Thanh Nguyen1,2, Guang Jia1,
Zarine Shah1, Mitva Patel1, Peter Wassenaar1,
Steffen Sammet1, Amir Mortazavi3, Karmal Pohar4,
Cathy Mojzisik1, Michael Knopp1
1Department of Radiology, The Ohio
State University, Columbus, OH, United States; 2Biophysics
Program, The Ohio State University, Columbus, OH, United States; 3Department
of Internal Medicine, The Ohio State University, Columbus, OH, United States;
4Department of Urology, The Ohio State University, Columbus, OH,
United States
This
on-going study evaluates the ability of Diffusion-Weighted MRI (DWI) and
Dynamic Contrast-Enhanced MRI (DCE-MRI) to diagnose bladder tumors and the
consistency between the two sequences. Preliminary results from this study
show that DWI and DCE-MRI are effective to detect bladder cancer. With these
promising preliminary results, the combination can be continued to study the
alteration of tumor characteristics after neoadjuvant therapy and the most
importantly to help stage bladder tumors. In addition, DWI performed with
high b-factors can be supportive to the differentiation of bladder tumors
from surrounding tissues.