Vijay
Pravin Shah1,2, Baris Turkbey2, Thomas Pohida3,
Haresh Mani4, Maria Merino4, Peter A. Pinto5,
Cheng Ruida3, Matthew McAuliffe3, Peter Choyke2,
Marcelino Bernardo1,6
1Imaging Physics, SAIC-Frederick, Inc,
Frederick, MD, United States; 2Molecular Imaging Program, National
Cancer Institute,, Bethesda, MD, United States; 3Division of
Computational Bioscience, CIT, National Institutes of Health, Bethesda, MD,
United States; 4Laboratory of Pathology, National Cancer
Institute, Bethesda, MD, United States; 5Urologic Oncology Branch,
National Cancer Institute, Bethesda, MD, United States; 6Molecular
Imaging Program, National Cancer Institute, Bethesda, MD, United States
Prostatectomy
specimens were processed using the Patient-specific MR-based molds (PSMRM) to
improve correlation clinical MR imaging with the histopathology. In this
study, we compare in vivo and ex vivo MRI of the prostate to evaluate performance
of the PSMRM. The volume and surface area were measured to quantitatively
evaluate fit of the specimen in the mold, while an experience radiologist
performed radiology evaluation. Prostate volume shrinkage ranged from 2-25%,
but we could observe good correlation between the in vivo and ex vivo MRI
for most cases.