Wei Liu1, Julien Senegas2, Baris
Turkbey3, Dagane Daar4, Marcelino Bernardo4,
Peter Choyke3
1Clinical Sites Research Program, Philips
Research North America, Briarcliff Manor, NY, United States; 2Sector
of Tomographic Imaging, Philips Research Europe, Hamburg, Germany; 3Molecular
Imaging Program, National Cancer Institute, Bethesda, MD, United States; 4Molecular
Imaging Program, National Cancer Institute, SAIC-Frederick Inc., Bethesda,
MD, United States
A
fast T2 mapping technique using multi-echo spin-echo sequence with four-fold
undersampling has been applied to characterize prostate T2 values in 23
patients. Utilizing the temporal and spatial correlation of T2 signal decay,
folding-free images were reconstructed at each echo time providing a series
of diagnostic images with variable T2-weighting. Quantitative T2 maps were
generated with very good reproducibility in clinical relevant scan time. T2
values of tumor tissues were significantly lower than the normal control
regions. Our results demonstrate this fast T2 relaxometry can provide an
effective approach for accelerated T2 quantification in prostate patients.