Sophie F. Riches1, Veronica A. Morgan2,
Sharon Giles2, Catherine Simpkin2, Nandita deSouza1
1Cancer Research UK and EPSRC Cancer
Imaging Centre, Institute of Cancer Research & Royal Marsden NHS
Foundation Trust, Sutton, Surrey, United Kingdom; 2Cancer Research
UK and EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust,
Sutton, Surrey, United Kingdom
Tumor
detection within the prostate depends on T2-weighted contrast. This study
compares T2 values at 3T and 1.5T and investigates differences in T2 contrast
with fractional volume of the peripheral zone (PZ). T2 values obtained at 3T
were not significantly different to
those at 1.5T for any prostate region. Patients with a low PZ to whole prostate volume showed
significantly reduced T2 in PZ compared to those with larger PZ
fractions. In patients with low
fractional PZ volume, therefore, T2 values of PZ may be indistinguishable
from tumor, reducing the ability to detect tumor within the PZ in these
patients.