Joakim Jonsson1, Mikael Karlsson1,
Magnus G. Karlsson2, Tufve Nyholm2
1Department of Radiation Sciences,
Radiation Physics, Ume University, Ume, Sweden; 2Department of
Radiation Physics, Ume University Hospital, Ume, Sweden
In
many cases where an organ of interest is free to move within the patient
anatomy, e.g. the prostate gland, normal image registration techniques are
insufficient. The patient external contour and bony anatomy will heavily
influence the registration, causing the actual organ of interest to be
misaligned. In order to overcome this problem, the registration can be
performed in such a way that the information available in the organ of
interest and regions in close proximity to it is more important to the
registration algorithm. This study evaluates the accuracy of such a
sub-volume based approach.