Mayumi Takeuchi1, Kenji Matsuzaki1,
Masafumi Harada1, Hiromu Nishitani1
1Department of Radiology, University of
Tokushima, Tokushima, Japan
We
evaluated 32 uterine corpus tumors (14 malignant including 11 endometrial
carcinomas and 3 myometrial tumors; 18 benign including 5 endometrial and 13
myometrial masses) by 1H-MR spectroscopy at 3T. Choline peaks were observed
in all 32 lesions, and tended to show higher peaks in malignant tumors. The
choline concentration in malignancy (8.77+/-1.91 mM) was significantly higher
than that in benign lesions (4.82+/-2.23 mM) (p<0.0001). Using a cut off
value of 7.00 mM for malignant lesions had a sensitivity of 93%, specificity
of 83%, PPV of 94%, and NPV of 81%.