Russell Norman Low1,2, Huanzhou Yu3,
Ann Shimakawa3, Lloyd Estkowski, Richard Ehman4
1Sharp and Children's MRI Center, San
Diego, CA, United States; 2San Diego Imaging, San Diego, CA,
United States; 3Applied Science Lab, General Electric Healthcare; 4Mayo
Clinic
Quantification
of diffuse liver disease adds a new dimension to hepatic MR imaging which can
provide critical information for diagnosis and for monitoring response to therapy.
We explore the implementation of a rapid breath-hold MR evaluation of liver
fibrosis using MR Elastography combined with a new multiecho Dixon technique
known as IDEAL Quant which quantifies liver iron assessed by R2* values and
fat fraction. In five breath holds this exam assesses liver fibrosis, R2*
correlated with iron content, and the percentage of fatty infiltration.