Andrew B. Rosenkrantz1, Pippa Storey1,
Ben Niver1, Cristina Hajdu2, Vivian S. Lee1
1Radiology, NYU Langone Medical Center,
New York, NY, United States; 2Pathology, NYU Langone Medical
Center, New York, NY, United States
8
patients with liver cirrhosis and 8 volunteers underwent liver MRI at 1.5T
that included repeated applications of an adjustable magnetization-transfer
contrast (MTC) sequence, with the MT pre-pulse offset frequency varying from
1000Hz to 3000Hz and the MT pre-pulse flip angle varying from 100 to
900. The magnetization transfer ratio
measured over the right lobe showed substantial overlap between healthy and
cirrhotic liver for all assessed MTC sequences, with none of the differences
being significant (p-values from 0.092 to 0.819). Our data suggests that, unlike the results
of previous studies, MTC imaging is unable to differentiate healthy and
cirrhotic liver.