Marina
Benito1, Alexia Rodrguez-Ruano2, Cristina Chavarrias1,
Paula Montesinos1, Manuel Desco1
1Unidad
de Medicina y Ciruga Experimental, Hospital General Universitario Gregorio
Maran, Madrid, Spain; 2Unidad de Medicina y Ciruga Experimental
, Hospital General Universitario Gregorio Maran, Madrid, Spain
SWI
allows to delineate the cerebral veins in
high quality, however during the MRI exam animals are anaesthetized.
Anesthetics make vary the venous contrast depending on the deepness of
anesthesia, but when using inhalated anesthesia the venous response on SWI also depends on
the partial pressure of oxygen (pO2) in the supplied gas. This study
investigates how the pressure of oxygen in the supplied gas affects the
venous contrast in SWI in order to study the microvasculature of the rat
brain.